What helps "Hypothiazide": reviews
What helps "hypothiazide"? This is a fairly frequent question. This article will discuss this diuretic drug. The instructions for use of this drug is prescribed that it should be taken with high blood pressure, heart failure, edema.
Tablets "Hypothiazide", being a powerful diuretic medicine, increase the excretion of sodium and chlorine from the body. Within two hours diuresis and natriuresis occur, reaching the highest level after about four hours. Indications for use of tablets "Hypothiazide" consider below.
In addition to the action of a diuretic, this drug also has a hypotensive effect. There are good reviews about this drug as a drug that is used to eliminate the symptoms of toxicosis in pregnant women. With prolonged use of this drug does not decrease its diuretic (diuretic) effect.
Release form and composition
Available in the form of tablets of 0.025 g and 0.1 g in a package of 20 and 200 pieces.
One tablet contains 25/100 mg of the active substance - hydrochlorothiazide. Auxiliary substances include: gelatin, corn starch, magnesium stearate, talc, lactose.
So, let's see what helps "hypothiazide."
"Hypothiazide" is prescribed for use in the following pathological conditions and ailments:
- portal hypertension;
- edema syndrome of various genesis;
- taking corticosteroid medicines;
- nephrotic syndrome;
- chronic kidney disease;
- acute glomerulonephritis;
- state of premenstrual stress;
- chronic heart failure.
In addition, the tablets "Hypothiazide" is used to control polyuria (with nephrogenic diabetes); with arterial hypertension (combining this drug with other antihypertensive drugs, in monotherapy); for the prevention of stone formation in the urinary system in patients predisposed to this disease.
These are the main indications for the use of "Hypothiazide".
The drug must be taken after eating, drinking water. The drug dosage must be selected individually. For the treatment of hypertension, the initial dosage of the drug is 25-50 mg per day (at a time). The antihypertensive effect begins to appear after three to four days. To achieve the best effect from taking this drug, treatment may take about three to four weeks. Hypertension is what Hypothiazide helps, but not only.
After taking the drug, the hypotensive effect may last for about a week. During premenstrual stress, the daily dosage is 25 mg. It should be applied from the onset of the first symptoms to the first day of the onset of menstruation. The initial daily dose of "Hypothiazide" in the presence of edema syndrome of different origin is 25-100 milligrams (it is allowed to divide the administration by two days).
In possible severe cases, the daily dosage of the drug can be increased to 200 mg. When the disease nephrogenic diabetes insipid "Gipotiazid" is prescribed daily for 50-150 mg (divided into several doses).Children from three to twelve years of dosing is selected personally, based on body weight. Usually, the pediatric dose is 1-2 mg per day per 1 kilogram of body weight. What helps "hypothiazide" - is clear. Does he have any contraindications?
According to the instructions for use, "Hypothiazide" should not be used with:
- severe liver disease;
- severe renal failure;
- in the presence of difficult controlled diabetes;
- I trimester of pregnancy and breastfeeding;
- refractory hyponatremia, hypokalemia, hypercalcemia;
- under the age of 3 years;
- with hypersensitivity to the constituent elements of the drug and to sulfonamide derivatives.
The purpose of this drug with caution is possible during pregnancy in the II and III trimesters, patients suffering from ischemia (IHD), cirrhosis of the liver, gout, lactose intolerance, if simultaneously applied cardiac glycosides and elderly patients. Contraindications and indications for the use of "Hypothiazide" we reviewed. What negative reactions can develop during reception?
Possible side effects
With the use of “Hypothiazide”, such side effects may occur as: anorexia, abnormal stool, cholestatic jaundice, pancreatitis, lethargy, confusion, delayed thinking, convulsions, excessive excitability, fatigue, muscle cramps on the background of hypercalcemia, hypomagnes, and hypokaliemia violation of heart rhythm, dry mouth, the appearance of thirst, unexplained fatigue or weakness, changes in the psyche, a sharp change in mood, possibly the appearance of cramps and muscle pain, nausea, short duration constant prices blurred vision, headaches, dizziness, paresthesia, renal dysfunction may decrease the potency, allergic reactions. It is important not only to be interested in what “Hypothiazide” helps, but also to carefully study the instructions for use in order to avoid undesirable consequences.
With a possible overdose
In case of overdose, the following symptoms may appear: due to rapid loss of fluid and electrolytes, tachycardia may appear, a decrease in blood pressure, shock, weakness, confusion, dizziness, pain in the calf muscles, feeling of fatigue, nausea, vomiting, severe thirst, polyuria, oliguria or anuria.
In case of overdose, it is necessary to induce vomiting, flush the stomach, then take activated charcoal. Control of the state of water and electrolyte balance (especially the level of potassium in the serum) and the work of the kidneys is required, until normal values are established. A special antidote does not exist.
What helps tablets "Hypothiazide", interests many.
The effect of using with other drugs
With a one-time treatment with lithium salts, it is possible to increase its toxicity and decrease renal clearance. It is not recommended to take "Gipotiazid" together with "Kolestiramin", because the combination of these drugs can lead to a decrease in the absorption of hydrochlorothiazide. With the combination of the drug under consideration with cardiac glycosides, the development of hypomagnesaemia and hypokalemia is possible.
The simultaneous use of this tool with corticosteroid drugs increases the degree of excretion of potassium. According to reviews of this drug, when used in combination with Amiodarone, the possibility of arrhythmia, which is associated with hypokalemia, increases. When taking a diuretic drug we are considering withOral hypoglycemic drugs develop hyperkalemia and decrease the effectiveness of the latter.
With long-term use of the drug should be monitored for clinical signs of violations of water and electrolyte balance, to a greater extent this applies to patients with impaired liver function, as well as suffering from a disease of the cardiovascular system. When using the drug, there is an enhanced excretion of magnesium and potassium ions, which entails the need to take medications in parallel with the treatment with “Hypothiazide”, which help to compensate them and prevent the deficiency of these minerals. So this is not the main question - from what does "Hypothiazide" help. Reviews confirm this.
Patients with impaired kidney function should periodically monitor creatinine clearance, if oliguria occurs, consult a doctor to stop taking the drug. Patients suffering from impaired liver function should use thiazides with caution, since the slightest deviations in the water-electrolyte balance and the level of ammonium in the blood serum often lead to hepatic coma.
With extreme caution it is necessary to take the drug in patients with severe coronary and cerebral sclerosis. With long-term treatment with this drug in patients with latent and manifest diabetes, it is required to periodically monitor the metabolism of carbohydrates and adjust the dosage of hypoglycemic drugs. Patients suffering from uric acid metabolism dysfunction should be under constant observation.
Occasionally prolonged therapy leads to pathological changes in the parathyroid glands. At the beginning of the drug intake, it is necessary to stop driving vehicles, and also to perform work that requires increased attention, the duration of these prohibitions is determined individually. This is confirmed by the drug "Hypothiazide" reviews.
Analogs of the drug
The main analogues are “Hydrochlorothiazide-SAR” and “Hydrochlorothiazide”. In addition to these analogues, there are medicines similar in pharmacological actions: "Torasemide", "Diuver", "Inspra", "Arifon", "Furosemide", etc.
Use during pregnancy
During pregnancy in the first trimester, the drug "Hypothiazide" is contraindicated due to the presence in its composition of the active component hydrochlorothiazide. If the possible benefit to the mother is greater than the risk to the health of the fetus, the prescription of this drug is allowed in the 2nd and 3rd trimesters. This is confirmed by the tool "Hypothiazid" reviews and instructions.
The active substance contained in the "Hypothiazide" can pass the placental barrier, which can lead to the development of newborn thrombocytopenia, jaundice and other consequences. During lactation, the active component is excreted along with the milk, interruption of breastfeeding is required, if there is a need to receive a diuretic.
How to store?
The drug should be stored in a dark place inaccessible to children, at a temperature not higher than 25 degrees. It is suitable under such storage conditions for 5 years.
Reviews of patients and doctors
According to the reviews of "Hypothiazide", it has a mild diuretic effect, if you follow the instructions in the application of the treatment regimen. This tool gently removes puffiness, while not removing beneficial substances from the body.
There is a certain group of women who use the hypothiazide pills for weight loss. Doctors are of the opinion that it is inappropriate to use the drug for such a purpose. Body weight may decrease due to the removal of fluid from the body, but then the weight begins to return. Use for this purpose does not affect the reserves of fat, in addition, it can harm because of dehydration, which leads to the loss of substances necessary for the body.
We told in detail how Hypothiazide helps.